Support for our body’s hormone infrastructure kicks off a healthy domino effect

For anyone whose aging (and who isn’t?!), we start noticing differences in our stress tolerance, weight, and even how well we heal after a workout. How can we push back at these unwanted symptoms of premature aging? The answer is supporting our body’s infrastructure that produces the needed hormones. What is this infrastructure? Our endocrine system. A healthy endocrine system will help us with the following and much more.


You may not be aware that “metabolism” refers to chemical reactions

within our cells which maintain their living state. 

When malnourished, how is our metabolism affected? Most people are aware of the negative effect it can have on our weight. Since one of the pivotal components of our metabolism is energy production, if our metabolism isn’t functioning well, we’ll feel it with fatigue and tiredness. Our metabolism also deals with fat transport, which can affect our organ health when we produce visceral fat on our organs. This can be a killer.

The remarkable thing is that nutrition and the availability of nutrients have a tangible impact on our metabolic rate. They can, in many instances, reverse these symptoms helping us to lose that dangerous visceral fat, maintain a good weight, have more energy, and have better organ health.

Nervous system function

Although the endocrine system isn’t directly linked to the nervous system, they are most undoubtedly dependent on each other. Their link is the hypothalamus, which controls many behaviors like stress responses, sleep, hunger, thirst, and even libido. This gland controls the pituitary gland, which regulates the release of hormones from other glands in the endocrine system. Talk about a domino effect!

Keeping our endocrine and nervous systems well-nourished can positively affect everything from our digestion, heart rate, tolerance to heat, and even our balance.

DNA synthesis and cell maintenance

Our cells need to be active and in good condition to do the many functions they are designed to do in our bodies.

Our DNA couldn’t be more important. It contains instructions that enable our bodies to be alive. But our DNA is easily damaged due to errors while replicating, free radical damage, or even UV radiation. However, our cells have specialized proteins that can repair these damages. Our DNA can be stimulated to action, or “synthesis,” and help us grow, develop, be healthy, and fight against premature aging and disease. Maintaining our cells can also aid tissue regeneration, growth, reproductive and digestive health, healing, and energy.

[For more information on the function of the endocrine system, please see this link published in August of 2021.]

So, how do we keep our endocrine system in the best shape possible, allowing it to provide the natural chemicals we need to be happy and healthy, keep our weight down, have healthy sex, and stave off brain fog? 

FGF SUPPORT is uniquely formulated with ingredients carefully chosen to provide maximum assistance to the endocrine system. 

Here are some of the ingredients and their historical benefits:


This excellent antioxidant-rich thistle is purported to lower blood sugar levels and improve digestion and heart and liver health. It is rich in fiber, folate, vitamin C, K, magnesium, phosphorus, potassium, and iron. 


This ancient medicinal herb has been used for over 3000 years to help reduce and manage stress, increase energy levels, and improve concentration. Studies have found quite encouraging results from ashwagandha usages, such as improvements in brain function, blood sugar, cholesterol and triglycerides, insulin production, and symptoms of anxiety and depression. In addition, the herb contains a high concentration of withanolides and withaferin. These components have been shown to fight against pain, irritation, tumor growth, and several types of cancer. 

Ashwagandha may also help increase testosterone levels, boost sperm quality, build muscle mass, reduce body fat, and increase physical stamina.


This trace element might play a role in carbohydrate, lipid, and protein metabolism by potentiating insulin action. It is being studied with regard to helping build muscle mass, weight loss, and glucose control.

Betaine HCL

Traditionally Betaine HCL is used for improving stomach pH, anemia, nutrient absorption, Gastroesophageal reflux disease (GERD) symptoms, food allergies, gallstone symptoms, and heart, joint, thyroid, and liver health.


The eleuthero plant has been used in Asia for over 2000 years as an immune booster, general stimulant, and adaptogen (a compound that helps the body adapt and handle stress). Additionally, studies indicate it can significantly lessen lactic acid and blood urea nitrogen buildup after physical activity and increase fat utilization. Increasing circulation also appears to positively affect the brain, physical performance, and wound and nerve healing. If that isn’t enough, it’s also been shown to reduce insulin resistance and is being considered for protocols in managing type 2 diabetes.


This nutrient supports cellular growth; is used by the body to produce fats that make up cellular membranes, impacts DNA synthesis, and can even affect gene expression. It is also converted into neurotransmitters that affect the nerves that help us regulate bodily functions such as breathing and heart rate. It also plays a role in multiple body functions and systems, such as liver function, circulatory and metabolic systems, brain development, and even muscle movement.


Inositol, a type of sugar rather than a vitamin, helps the body process insulin and bind neurotransmitters. Due to its ability in this area, it seems to have great potential for mental health concerns such as panic disorders and depression. It may very well aid in controlling risk factors associated with metabolic syndrome and lowering triglycerides, cholesterol, blood pressure, and blood sugar levels.


This critical amino acid, a building block for our bodies to make proteins, is unique. It can convert into sulfur-containing molecules with essential functions, such as glutathione, taurine, S-adenosylmethionine (SAM), and creatine. Some of these molecules can alter DNA for the better. Studies on animals show them slowing the rate of aging and increasing lifespan. 

Milk Thistle

Milk thistle shows potential as a complementary therapy for various conditions, including liver disease, cancer, and diabetes. In addition, initial studies indicate resistance to oxidative stress, which may help improve cognition and brain degenerative conditions.


Typically, pancreatin, which helps break foods down and convert them to energy, is produced in the pancreas. When sufficient pancreatic enzymes aren’t present, gas, bloating, indigestion, weight loss, and other digestive issues can crop up. Pancreatin’s enzymes: amylase, lipase, and protease, work together to better digestion and energy.

Sage Leaf

Sage is an herb with promising health benefits and belongs to the mint family. Its antimicrobial nature may help support oral health. Sage’s high antioxidant count may also aid brain functionlower blood sugar and cholesterol levels, and fight against disease-causing oxidative stress. 

Vitamin C

We hear so much about vitamin C’s stellar benefits to the immune system that its other benefits are often overshadowed. Vitamin C also plays into the function of the adrenal cortex and medulla. In addition, studies indicate that individuals with fatigue and depression who were low in vitamin C experienced an improvement in mood and anxiety when supplemented with vitamin C.

Vitamin B3 (niacinamide)

As one of the eight essential B vitamins, B3 is a significant player in cellular metabolism, cell signaling, and making and repairing DNA. For this reason, the list of possible conditions it can positively impact is long: arthritis, heart health, psoriasis, non-melanoma, skin cancer, diabetes, brain function, and many others

Vitamin B5 (pantothenic acid)

Vitamin B5 is arguably one of the most essential of the B vitamins. It is needed to convert fats and protein into energy, manufacture red blood cells to carry oxygen throughout the body, and help the adrenals produce hormones affecting our sexual health and stress endurance. Its therapeutic benefits also aid in digestive, heart, and skin health. 

Since the endocrine system impacts just about everything in the body, including our mood, enjoyment of life, physical stamina, and energy level, it’s something to invest in and maintain. A little nourishment will go a long way to keep this delicate system working at peak efficiency.

As always, FGF USA products are thoughtfully sourced, made in the USA, at FDA-inspected GMP facilities, and are GMO-free.


  • Kim Ann Zimmerman, Endocrine System: Facts, Functions and Diseases, Live Science, 2018.
  • P Patak, HS Willenberg, S R Bornstein, Vitamin C is an important cofactor for both adrenal cortex and adrenal medulla, PMID 15666839, 30 Nov 2004.
  • Brent A Bauer, MD, Can vitamin C improve your mood?, Mayo Clinic, FAQ-20058271, 10 Nov 2020.
  • Mohammad Reza Namazi, Nicotinamide: a potential addition to the anti-psoriatic weaponry, PMID: 12890690, 17 Aug 2003.
  • Kerri-Ann Jennings, MS, RD, 9 Science-Based Benefits of Niacin (Vitamin B3), HL, 26 Nov 2018.
  • Vitamin B5 (Pantothenic acid), Mount Sinai, NY.
  • Pantothenic Acid (Oral Routine), Mayo Clinic, 1 Feb 2021. 
  • Megan Ware, RDN, LD, The benefits and risks of chromium, MNT, 22 May 2017.
  • Chromium, HIH Fact Sheet for Health Professionals, 29 Mar 2021.
  • C M Seiler, et al, Randomized clinical trial: a 1-week, double-blind, placebo-controlled study of pancreatin 25 000 Ph. Eur. Minimicrospheres (Creon 25000 MMS) for pancreatic exocrine insufficiency after pancreatic surgery, with a 1-year open-label extension, WOL, 10.1111, apt. 12236, 5 Feb 2013.
  • Adrian White, Should I Take Pancreatic Supplements?, Healthline, 18 Sept 2018. 
  • Miho Hatanaka, RDN, LD, 12 potential health benefits of eleuthero, MNT, 23 Aug 2017.
  • Jip Kuo, et al, The effect of eight weeks of supplementation with Eleutherococcus senticusus on endurance capacity and metabolism in human, PMID: 21793317, 30 Apr 2010.
  • Rena Goldman, What are the benefits of ashwagandha? MNT, 29 Sept 2020.
  • Mohammad Hossein Mirjalili, et al, Steroidal lactones from Withania somnifera, an ancient plant for novel medicine, PMID: 19633611, 3 Jul 2009.
  • Franziska Spritzler, 12 Proves Health Benefits of Ashwagandha, HL, 3 Nov 2019.
  • Jamie Eske, Katherine Marengo, LDN, RD, Everything you need to know about choline, MNT, 25 Nov 2019.
  • Elsawy, G., et al, Effect of choline supplementation on rapid weight loss and biochemical variables among female taekwondo and judo athletes, PMID: 4096089, 2014.
  • Mary Jane Brown, PhD, RD, What is Choline? An Essential Nutrient With Many Benefits, HL, 7 Dec 2018.
  • John T Brosnan, Margaret E Brosnan, The Sulfur-Containing Amino Acids: An Overview, JN-136.6.1636S, Jun 2006.
  • Grant Tinsley, PhD, Methionine: Functions, Food Sources and Side Effects, HL, 13 Apr 2018.
  • Yago MR, Frymoyer A, Benet LZ, et al. The use of betaine HCl to enhance dasatinib absorption in healthy volunteers with rabeprazole-induced hypochlorhydriaAAPS J. 2014;16(6):1358-1365. doi:10.1208/s12248-014-9673-9
  • Kines K, Krupczak T. Nutritional interventions for gastroesophageal reflux, irritable bowel syndrome, and hypochlorhydria: A case reportIntegr Med (Encinitas). 2016;15(4):49-53.
  • Yago MR, Frymoyer AR, Smelick GS, et al. Gastric reacidification with betaine HCl in healthy volunteers with rabeprazole-induced hypochlorhydriaMol Pharm. 2013;10(11):4032-4037. doi:10.1021/mp4003738
  • Lana Burgess, Debra Rose Wilson, PhD, MSN, RN, What are the benefits of milk thistle?, MNT, 20 Dec 2017.
  • Yu Guo, et al, Silymarin improved diet-induced liver damage and insulin resistance by decreasing inflammation in mice, PMID: 27387273, Dec 2016.
  • Kendra Cherry, The Nervous and Endocrine Systems, VWM/Biological Psychology, 18 Mar 2022.
  • Marianne Belleza, RN, Endocrine System Anatomy and Physiology, Nurselabs, 11 Feb 2021.
  • Donatella Negro, et al, Polyphenol compounds in artichoke plant tissues and varieties, PMID: 22251096, Feb 2012.
  • May Jane Brown, PhD, RD, Top 8 Health Benefits of Artichokes and Artichoke Extract, HL, 16 Jan 2019.
  • JillSeladi-Schulman, Ph.D., DNA Explained and Explored, 11 Feb 2022.
  • Ahmad Ghorbani, et al, Pharmacological properties of Salvia officinalis and its components, PMID: 29034191, 13 Jan 2017.
  • Carla M Sa, et al, Sage tea drinking improves lipid profile and antioxidant defenses in humans, PMID: 19865527, 9 Sept 2009. 
  • Megan Ware, RDN, LD, Everything you need to know about sage, MNT, 10 Jan 2018.
  • Joseph Lamer, D-Chiro-Inositol-Its Functional Role in Insulin Action and its Deficit in Insulin Resistance, PMID: 11900279, 2002.
  • Makayla Meixner, MS, RDN, Inositol: Benefits, Side Effects and Dosage, HL, 15 Aug 2018.
  • Dan Brennan, MD, Health benefits of Inositol, WMD, 19 Nov 2020.